Analysis on Application Approval of New Food Additives in China in 2022 - Regulatory News - Food & Food Contact Materials - CIRS Group

China,Food,Analysis,New,Additive,Application,Approval

By the end of December 2022, the National Health Commission of the People's Republic of China (NHC) issued three announcements (No. 1 of 2022,No. 2 of 2022,No. 5 of 2022) in the form of "Three New Foods" with75products approved, including new food raw materials (novel food), new food additives and food-related products (new food contact substances). Among them,32kinds of new food additives (including expanded use) were approved.

According to the NHC and the China National Center for Food Safety Risk Assessment (CFSA) websites, in 2022, a total of72new food additives applications were accepted, and45new food additives (including expanded use) passed the technical evaluation and were issued for public comments.

This article provides you with detailed information about the acceptance and approval of new food additives in China in 2022.

1. List of new food additives applications in 2022 (72 types)

In 2022, a total of 72 new food additives (including expanded use) applications were accepted by the NHC. Since the acceptance code all begin with "卫食添新申字", there is no distinction between domestic and imported products.

Among them, monascus yellow pigment was not granted the administrative license onMarch 8, 2022. Rebaudioside A, steviol glycosides, stevia extract, 6S-5-methyltetrahydrofolate calcium, serine protease and pyrrolidine -[1,2e] -4h-2, 4-dimethyl-1,3, 5-dithiazide were not granted the administrative license onAugust 16, 2022.Nucleotide was not granted the administrative license onSeptember 14, 2022.

No.	Acceptance date	Acceptance Code	Name of New Food Additives
1	2022.01.06	卫食添新申字(2022)第0001号	Carboxypeptidase
2	2022.01.10	卫食添新申字(2022)第0002号	Monascus yellow pigment
3	2022.01.30	卫食添新申字(2022)第0003号	Carmine cochineal
4	2022.02.11	卫食添新申字(2022)第0004号	Rebaudioside A
5	2022.02.11	卫食添新申字(2022)第0005号	Stevia glycosides
6	2022.02.11	卫食添新申字(2022)第0006号	Stevia extract
7	2022.02.16	卫食添新申字(2022)第0007号	Magnesium stearate
8	2022.03.03	卫食添新申字(2022)第0008号	L-alanine
9	2022.03.07	卫食添新申字(2022)第0009号	Xylanase
10	2022.03.07	卫食添新申字(2022)第0010号	Aminopeptidase
11	2022.03.08	卫食添新申字(2022)第0011号	L-leucine
12	2022.03.08	卫食添新申字(2022)第0012号	L-isoleucine
13	2022.03.08	卫食添新申字(2022)第0013号	L-valine
14	2022.03.21	卫食添新申字(2022)第0014号	6S-5-methyltetrahydrofolate calcium
15	2022.04.02	卫食添新申字(2022)第0015号	Maltose alpha-amylase
16	2022-04-26	卫食添新申字(2022)第0016号	Lactase (beta-galactosidase)
17	2022.04.28	卫食添新申字(2022)第0017号	Phospholipase A2
18	2022.05.10	卫食添新申字(2022)第0018号	Serine protease
19	2022.05.10	卫食添新申字(2022)第0019号	Serine protease
20	2022.05.10	卫食添新申字(2022)第0020号	Xylanase
21	2022.05.23	卫食添新申字(2022)第0021号	2-hexyl pyridine
22	2022.05.26	卫食添新申字(2022)第0022号	L-cystine
23	2022.05.26	卫食添新申字(2022)第0023号	L-cysteine hydrochloride monohydrate
24	2022.05.26	卫食添新申字(2022)第0024号	L-lysine acetate
25	2022.05.26	卫食添新申字(2022)第0025号	L-histidine
26	2022.05.26	卫食添新申字(2022)第0026号	L-threonine
27	2022.05.26	卫食添新申字(2022)第0027号	L-cysteine hydrochloride
28	2022.05.26	卫食添新申字(2022)第0028号	L-cysteine
29	2022.05.26	卫食添新申字(2022)第0029号	L-phenylalanine
30	2022.05.26	卫食添新申字(2022)第0030号	L-lysine hydrochloride
31	2022.05.26	卫食添新申字(2022)第0031号	L- histidine hydrochloride monohydrate
32	2022.05.27	卫食添新申字(2022)第0032号	Pyrrolidino -[1,2e] -4h-2,4-dimethyl-1,3,5-dithiazide
33	2022.06.02	卫食添新申字(2022)第0033号	D-psicose 3-epimerase
34	2022.06.09	卫食添新申字(2022)第0034号	Rock mineral selenium
35	2022.06.13	卫食添新申字(2022)第0035号	L-selenomethyl selenocysteine
36	2022.06.13	卫食添新申字(2022)第0036号	Ammonium glycyrrhizinate
37	2022.06.13	卫食添新申字(2022)第0037号	Acesulfame potassium
38	2022.06.20	卫食添新申字(2022)第0038号	Magnesium lactate
39	2022.06.28	卫食添新申字(2022)第0039号	Sodium acetate
40	2022.06.28	卫食添新申字(2022)第0040号	Fumaric acid
41	2022.07.04	卫食添新申字(2022)第0041号	Lactulose
42	2022.07.04	卫食添新申字(2022)第0042号	Lactulose
43	2022.07.06	卫食添新申字(2022)第0043号	Nucleotide
44	2022.07.11	卫食添新申字(2022)第0044号	Sucralose
45	2022.07.12	卫食添新申字(2022)第0045号	L-serine
46	2022.07.12	卫食添新申字(2022)第0046号	L-Aspartic acid
47	2022.07.12	卫食添新申字(2022)第0047号	L(-)-Proline
48	2022.07.12	卫食添新申字(2022)第0048号	L-lysine-l-glutamic acid dihydrate
49	2022.07.12	卫食添新申字(2022)第0049号	L-citrulline
50	2022.07.12	卫食添新申字(2022)第0050号	L-potassium glutamate monohydrate
51	2022.07.12	卫食添新申字(2022)第0051号	L-glutamic acid
52	2022.07.12	卫食添新申字(2022)第0052号	L-glutamine
53	2022.07.12	卫食添新申字(2022)第0053号	L-lysine-L-aspartic acid
54	2022.07.12	卫食添新申字(2022)第0054号	L-ornithine hydrochloride
55	2022.07.12	卫食添新申字(2022)第0055号	N-acetyl-L-cysteine
56	2022.07.12	卫食添新申字(2022)第0056号	Glycine
57	2022.07.12	卫食添新申字(2022)第0057号	L-lysine monohydrate
58	2022.07.12	卫食添新申字(2022)第0058号	L-calcium glutamate tetrahydrate
59	2022.07.12	卫食添新申字(2022)第0059号	L-magnesium aspartate dihydrate
60	2022.07.12	卫食添新申字(2022)第0060号	Sodium N-cyclohexyl sulfamate (Also called cyclamate)
61	2022.07.13	卫食添新申字(2022)第0061号	Potassium glycyrrhizinate
62	2022.07.13	卫食添新申字(2022)第0062号	Tripotassium glycyrrhizinate
63	2022.07.15	卫食添新申字(2022)第0063号	lysophospholipase
64	2022.07.15	卫食添新申字(2022)第0064号	Potassium hydrogen tartrate
65	2022.08.12	卫食添新申字(2022)第0065号	vitamin E
66	2022.08.17	卫食添新申字(2022)第0066号	gardenia yellow
67	2022.08.17	卫食添新申字(2022)第0067号	Riboflavin
68	2022.08.23	卫食添新申字(2022)第0068号	L- lysine
69	2022.08.30	卫食添新申字(2022)第0069号	Curdlan
70	2022.09.02	卫食添新申字(2022)第0070号	Mycelial fermentation of Cordyceps sinensis
71	2022.09.05	卫食添新申字(2022)第0071号	Vanillin (fermentation)
72	2022.09.14	卫食添新申字(2022)第0072号	Cellulase

2. List of new food additives issued for public comments in 2022 (45 types)

In 2022, 45 new food additives passed the technical review of the CFSA and were issued for public comments, including 13 new food enzymes, three new food processing aids (including expanded use), one new flavor for food, 16 new nutrition enhancers, four existing nutrition enhancers with expanded use, one new food additive and seven existing food additives with expanded use.

Among them, carmine cochineal, aminopeptidase, xylanase, carboxypeptidase, phospholipase A2, lactase (beta-galactosidase), and D-psicose 3-epimerase which were accepted in 2022, the other seven products applications were accepted by NHC in 2021.

2.1 List of new food enzymes (13 types)

No	Name	Source	Donor	Approval status (By the end of December 2022)
1	β-glucanase	Bacillus subtilis	Bacillus subtilis	Accepted on September 17, 2022, Acceptance number: 卫食添新申字(2021)第0040号. Passed the technical review and issued for public comments onJanuary 29, 2022, and officially approved on May 11, 2022, according toNo. 2 of 2022.
2	Protease	Bacillus subtilis	Alkalihalobacillus clausii	Its acceptance information could not be confirmed. Passed the technical review and issued for public comments onJanuary 29, 2022, and officially approved on May 11, 2022, according toNo. 2 of 2022.
3	Trehalase	Trichoderma reesei	Trichoderma reesei	Accepted on September 17, 2022, Acceptance number: 卫食添新申字(2021)第0041号. Passed the technical review and issued for public comments onJanuary 29, 2022, and officially approved on May 11, 2022, according toNo. 2 of 2022.
4	Lactase	Aspergillus niger	Aspergillus oryzae	Accepted on November 9, 2022, Acceptance number: 卫食添新申字(2021)第0053号. Passed the technical review and issued for public comments onApril 15, 2022, and officially approved on September 7, 2022, according toNo. 5 of 2022.
5	Aminopeptidase	Aspergillus oryza	Aspergillus oryza	Accepted on March 7, 2022, Acceptance number: 卫食添新申字(2022)第0010号. Passed the technical review and issued for public comments onJuly 1, 2022. It has not been officially approved.
6	Xylanase	Bacillus licheniformis	Bacillus licheniformis	Accepted on March 7, 2022, Acceptance number:卫食添新申字(2022)第0009号. Passed the technical review and issued for public comments onJuly 1, 2022, It has not been officially approved.
7	Carboxypeptidase	Aspergillus oryzae	Aspergillus oryza	Accepted on January 6, 2022, Acceptance number: 卫食添新申字(2022)第0001号. Passed the technical review and issued for public comments onJuly 1, 2022. It has not been officially approved.
8	Deaminase	Aspergillus oryza	-	Accepted on April 30, 2020, Acceptance number: 卫食添新申字(2020)第0020号. Passed the technical review and issued for public comments onJuly 1, 2022. It has not been officially approved.
9	Protease	Trichoderma reesei	Malbranchea sulfurea	Its acceptance information could not be confirmed. Passed the technical review and issued for public comments onOctober 28, 2022. It has not been officially approved.
10	Phospholipase A2	Trichoderma reesei	Aspergillus fumigatus	Accepted on April 28, 2022, Acceptance number: 卫食添新申字(2022)第0017号. Passed the technical review and issued for public comments onOctober 28, 2022. It has not been officially approved.
11	Maltogenic amylase	Saccharomyces cerevisiae	Geobacillus stearothermophilus	Its acceptance information could not be confirmed. Passed the technical review and issued for public comments onOctober 28, 2022. It has not been officially approved.
12	Lactase（beta-galactosidase）	Papiliotrema terrestris	-	Accepted on April 26, 2022, Acceptance number: 卫食添新申字(2022)第0016号. Passed the technical review and issued for public comments onOctober 28, 2022. It has not been officially approved.
13	D-psicose 3-epimeras	Bacillus subtil	Ruminococcus sp. CAG55	Accepted on June 2, 2022, Acceptance number: 卫食添新申字(2022)第0033号. Passed the technical review and issued for public comments onDecember 8, 2022. It has not been officially approved.

Note: The quality specification of enzymes should meet the requirements of the "National Food Safety Standard, Food Additives and Enzyme" (GB 1886.174).

2.2 List of new food processing aid (one type)

Name

Function

Food name/category

Maximum level in grams per kilogram (g/kg)

Approval Status

(By the end of December 2022)

Sodium sulfide pentahydrate

Deacidizing agent, decolorizing agent, settling agent

Salt production process

0.065

Accepted on July 7, 2021, Acceptance number: 卫食添新申字(2021)第0030号.

Passed the technical review and issued for public comments onJanuary 29, 2022, and officially approved on May 11, 2022, according toNo. 2 of 2022.

2.3 List of existing food processing aids with expanded use (two types)

Name

Function

Usage scope

Approval Status

(By the end of December 2022)

Polydimethyl siloxane and emulsion

Antifoaming agent

Collagen casings processing technology

Its acceptance information could not be confirmed.

Passed the technical review and issued for public comments onJuly 1, 2022.

It has not been officially approved.

Magnesium stearate

Lubricant, release agent, anti-sticking agent

Effervescent tablet pressing process

Accepted on February 16, 2022, Acceptance number: 卫食添新申字(2022)第0007号.

Passed the technical review and issued for public comments onJuly 1, 2022.

It has not been officially approved.

2.4 List of new flavor (one type)

Name

Function

Food name/category

Maximum level grams per liter (g/L)

Approval Status

(By the end of June 2022)

2-hexylpyridine

flavoring

Used in various foods after being formulated into flavors (Except for the food category in Table B1 of GB 2760-2014)

Appropriate level as required in production

Accepted on May 23, 2022, Acceptance number: 卫食添新申字(2022)第0021号.

Passed the technical review and issued for public comments onOctober 28, 2022.

It has not been officially approved.

2.5 List of new food nutrition enhancers (16 types)

No	Name	Category number	Food name/category	Maximum level	Approval Status (By the end of December 2022)
1	2'- fucosyllactose	01.03.02	Modified milk powder (limited to milk powder for children)	0.7-2.4 g/L (Count as pure products. In terms of ready-to-eat state, for powdery products, the level of use should be increased by brewing time.) When mixed with Lacto-N-neotetraose, oligo-galactose, oligofructose, polyfructose and raffinose, the total amount of 2'- fucosyllactoseshall must not exceed 64.5 (g/kg)	Accepted on October 18, 2021, Acceptance number: 卫食添新申字(2021)第0048号, and accepted on November 3, 2021, Acceptance number: 卫食添新申字(2021)第0050号. Passed the technical review and issued for public comments onApril 15, 2022andOctober 28, 2022, It has not been officially approved.
		13.01.01	Infant formula foods
		13.01.02	Older infants and young children formula
		13.01.03	Infant formula food for special medical purposes
2	L-alanine	13.01.03 Infant formula food for special medical purpose: Execute with reference to GB 25596; 13.03 Formula foods for special medical purposes (except for the varieties involved in 13.01): Execute with reference to GB 29922.			Its acceptance information could not be confirmed. Passed the technical review and issued for public comments onJuly 1, 2022. It has not been officially approved.
3	L-Arginine Hydrochloride	13.01.03 Infant formula food for special medical purpose: Execute with reference to GB 25596; 13.03 Formula foods for special medical purposes (except for the varieties involved in 13.01): Execute with reference to GB 29922.			Accepted on November 16, 2021, Acceptance number: 卫食添新申字(2021)第0055号. Passed the technical review and issued for public comments onJuly 1, 2022. It has not been officially approved.
4	L-selenomethyl selenocysteine	The application range and dosage of L-Se-methyl selenocysteine are consistent with the provisions of selenium approved in GB14880 "National Food Safety Standard for the Use of Food Nutrition Enhancer".			Accepted on June 13, 2022, Acceptance number: 卫食添新申字(2022)第0035号. Passed the technical review and issued for public comments onAugust 19, 2022. It has not been officially approved.
5	L-Cysteine	13.01.01 Infant formula: Execute with reference to GB 10765； 13.01.02 Older infants and toddler formula (Older infants formula only): Execute with reference to GB 10766； 13.01.03 Infant formula food for special medical purpose: Execute with reference to GB 25596; 13.03 Formula foods for special medical purposes (except for the varieties involved in 13.01): Execute with reference to GB 29922			Accepted on May 26, 2022, Acceptance number: 卫食添新申字(2022)第0028号； Passed the technical review and issued for public comments onAugust 19, 2022. It has not been officially approved.
6	L-Cysteine Hydrochloride Monohydrate				Accepted on May 26, 2022, Acceptance number: 卫食添新申字(2022)第0023号. Passed the technical review and issued for public comments onAugust 19, 2022. It has not been officially approved.
7	L-cysteine hydrochloride	13.01.01 Infant formula: Execute with reference to GB 10765； 13.01.02 Older infants and toddler formula (Older infants formula only): Execute with reference to GB 10766； 13.01.03 Infant formula food for special medical purpose: Execute with reference to GB 25596; 13.03 Formula foods for special medical purposes (except for the varieties involved in 13.01): Execute with reference to GB 29922.			Accepted on May 26, 2022, Acceptance number: 卫食添新申字(2022)第0027号. Passed the technical review and issued for public comments onAugust 19, 2022. It has not been officially approved.
8	L-Cystine				Accepted on May 26, 2022, Acceptance number: 卫食添新申字(2022)第0022号. Passed the technical review and issued for public comments onAugust 19, 2022. It has not been officially approved.
9	L-Histidine				Accepted on May 26, 2022, Acceptance number: 卫食添新申字(2022)第0025号. Passed the technical review and issued for public comments onAugust 19, 2022. It has not been officially approved.
10	L-Histidine Hydrochloride Monohydrate				Accepted on May 26, 2022, Acceptance number: 卫食添新申字(2022)第0031号. Passed the technical review and issued for public comments onAugust 19, 2022. It has not been officially approved.
11	L-Lysine Hydrochloride	13.01.01 Infant formula: Execute with reference to GB 10765； 13.01.02 Older infants and toddler formula (Older infants formula only): Execute with reference to GB 10766； 13.01.03 Infant formula food for special medical purpose: Execute with reference to GB 25596; 13.03 Formula foods for special medical purposes (except for the varieties involved in 13.01): Execute with reference to GB 29922			Accepted on May 26, 2022, Acceptance number: 卫食添新申字(2022)第0030号. Passed the technical review and issued for public comments onAugust 19, 2022. It has not been officially approved.
12	L-Lysine acetate				Accepted on May 26, 2022, Acceptance number: 卫食添新申字(2022)第0024号. Passed the technical review and issued for public comments onAugust 19, 2022. It has not been officially approved.
13	L-Phenylalanine				Accepted on May 26, 2022, Acceptance number: 卫食添新申字(2022)第0029号. Passed the technical review and issued for public comments onAugust 19, 2022. It has not been officially approved.
14	L-Threonine				Accepted on May 26, 2022, Acceptance number: 卫食添新申字(2022)第0026号. Passed the technical review and issued for public comments onAugust 19, 2022. It has not been officially approved.
15	Lacto-N-neotetraose	01.03.02	Modified milk powder (limited to milk powder for children)	0.2-0.6 g/L (Count as pure products – ready-to-eat state, for powdery products, the level of use should be increased by the brewing time) When mixed with 2’-FL , oligo-galactose, oligofructose, polyfructose and raffinose, the total amount of Lacto-N-neotetraose must not exceed 64.5 g/kg	Accepted on October 18, 2021, Acceptance number: 卫食添新申字(2021)第0049号. Passed the technical review and issued for public comments onOctober 28, 2022. It has not been officially approved.
		13.01.01	Infant formula foods
		13.01.02	Older infants and young children formula
		13.01.03	Infant formula food for special medical purposes
16	Magnesium lactate	The application range and dosage of magnesium lactate are consistent with the provisions of magnesium approved in GB14880 "National Food Safety Standard for the Use of Food Nutrition Enhancer".			Accepted on June 20, 2022, Acceptance number: 卫食添新申字(2022)第0038号. Passed the technical review and issued for public comments onDecember 8, 2022. It has not been officially approved.

2.6 List of food nutrition enhancers with expanded use (four types)

No	Name	Category number	Food name/category	Maximum level	Approval Status (By the end of December 2022)
1	Vitamin B1	14.04.02.01	beverages for special uses (including sports drinks and nutrient drinks.)	2 mg/kg~5 mg/kg	Its acceptance information could not be confirmed. Passed the technical review and issued for public comments onDecember 8, 2022. It has not been officially approved.
2	Vitamin B2	14.04.02.01	beverages for special uses (including sports drinks and nutrient drinks.)	2 mg/kg~5 mg/kg	Accepted on March 26, 2014, Acceptance number: 卫食添新申字(2014)第0013号； Passed the technical review and issued for public comments onDecember 8, 2022, It has not been officially approved.
3	Taurine	14.04.02.01	beverages for special uses (including sports drinks and nutrient drinks.)	0.1 g/kg~0.6 g/kg	Its acceptance information could not be confirmed. Passed the technical review and issued for public comments onDecember 8, 2022, It has not been officially approved.
4	Ascorbic palmitate (Enzymatic)	The application range and dosage of ascorbic palmitate are consistent with the provisions of vitamin C approved in GB14880 "National Food Safety Standard for the Use of Food Nutrition Enhancer".			Its acceptance information could not be confirmed. Passed the technical review and issued for public comments onDecember 8, 2022. It has not been officially approved.

2.7 List of new food additive (1 type)

Name

Function

Category number

Food name/category

Maximum level

Approval Status

(By the end of December 2022)

Potassium Polyaspartate

Stabilizer and coagulator

15.03.01

Wine

0.3 g/L

Accepted on May 9, 2020, Acceptance number: 卫食添新申字(2020)第0024号.

Passed the technical review and issued for public comments onDecember 28, 2022.

It has not been officially approved.

2.8 List of food additives with expanded use (seven types)

No	Name	Function	Category number	Food name /category	Maximum level (g/kg)	Approval Status (By the end of December 2022)
1	Potassium acesulfame	Sweetener	07.03	Crackers	0.6	Accepted on June 4, 2021, Acceptance number: 卫食添新申字(2021)第0022号. Passed the technical review and issued for public comments onJanuary 29, 2022, and officially approved on May 11, 2022, according toNo. 2 of 2022.
2	Carmine cochineal	Colorant	08.02.01	Conditioned meat products (raw meat with added ingredients)	0.08 (Count as carminic acid)	Accepted on January 30, 2022, Acceptance number: 卫食添新申字(2022)第0003号. Passed the technical review and issued for public comments onApril 15, 2022, and officially approved on September 7, 2022, according toNo. 5 of 2022.
3	Fumaric acid	Acidity regulator	08.02.02Cured meat product (brined meat, preserved pork, preserved duck, Chinese-style ham, and Chinese sausage) 08.03.02Smoked, baked, or grilled meat 08.03.03Fried meat 08.03.05Meat enema 09.02.02Frozen coated seafood product 09.04.02Cooked or fried seafood product 09.04.03Smoked or grilled seafood product		Appropriate level as required in production	Accepted on June 28, 2022, Acceptance number: 卫食添新申字(2022)第0040号. Passed the technical review and issued for public comments onAugust 19, 2022. It has not been officially approved.
4	Sodium acetate	Acidity regulator			Appropriate level as required in production	Accepted on June 28, 2022, Acceptance number: 卫食添新申字(2022)第0039号. Passed the technical review and issued for public comments onAugust 19, 2022. It has not been officially approved.
5	Sodium N-cyclohexyl sulfamate (Also called cyclamate)	Sweetener	07.04	Fillings and topping syrups for bakeries (fillings of crackers only)	2.0 (In terms of cyclohexyl sulfamic acid)	Accepted on July 12, 2022, Acceptance number: 卫食添新申字(2022)第0060号. Passed the technical review and issued for public comments onOctober 28, 2022. It has not been officially approved.
5	Sodium N-cyclohexyl sulfamate (Also called cyclamate)	Sweetener	16.06	Puffed food	0.2 (In terms of cyclohexyl sulfamic acid)
6	Vitamin E	Antioxidant	06.03.02.04	Batters (e.g. batters for fish or poultry), breaded, frying powder	0.2	Its acceptance information could not be confirmed. Passed the technical review and issued for public comments onOctober 28, 2022. It has not been officially approved.
7	Ascorbic palmitate (Enzymatic)	Antioxidant	06.07	Instant wheat or rice product	0.2	Its acceptance information could not be confirmed. Passed the technical review and issued for public comments onOctober 28, 2022. It has not been officially approved.

3. List of approved new food additives in 2022 (32 types)

In 2022, 32 types of new food additives were approved by the NHC, which includes 13 new enzymes for the food industry, one new food additive, one new processing aid, one new food nutrition enhancer, 13 existing food additives with expended use, and three processing aids with expanded use. The relevant information is as follows:

3.1 List of approved new food enzymes (13 types)

No	Name	Source	Donor	Acceptance information, public comment, and approval announcements (By the end of December 2022)
1	Phospholipase A1	Aspergillus oryzae	Valsaria rubricosa	Accepted on March 26, 2021, Acceptance number: 卫食添新申字(2021)第0013号. Passed the technical review and issued for public comments onAugust 6, 2021, and officially approved on March 1, 2022, according toNo. 1 of 2022.
2	Maltogenic amylase	Bacillus licheniformis	Geobacillus stearothermophilus	Accepted on March 19, 2021, Acceptance number:卫食添新申字(2021)第0014号. Passed the technical review and issued for public comments onAugust 6, 2021, and officially approved on March 1, 2022, according toNo. 1 of 2022.
3	Glucose oxidase	Trichoderma reesei	Penicilliun amagasakiense	Accepted on November 10, 2020, Acceptance number: 卫食添新申字(2020)第0068号. Passed the technical review and issued for public comments onAugust 6, 2021, and officially approved on March 1, 2022, according toNo. 1 of 2022.
4	Lipase	Trichoderma reesei	Aspergillus niger var. tubingensis	Accepted on March 22, 2021, Acceptance number: 卫食添新申字(2021)第0015号. Passed the technical review and issued for public comments onAugust 6, 2021, and officially approved on March 1, 2022, according toNo. 1 of 2022.
5	β-uctofuranosidase	Aspergillus fijiensis	-	Accepted on May 26, 2020, Acceptance number: 卫食添新申字(2020)第0027号. Passed the technical review and issued for public comments onOctober 21, 2021, and officially approved on May 11, 2022, according toNo. 2 of 2022.
6	β-glucanase	Bacillus subtilis	Bacillus subtilis	Accepted on September 17, 2021, Acceptance number: 卫食添新申字(2021)第0040号. Passed the technical review and issued for public comments onJanuary 29, 2022, and officially approved on May 11, 2022, according toNo. 2 of 2022.
7	Protease	Bacillus subtilis	Alkalihalobacillus clausii	Its acceptance information could not be confirmed. Passed the technical review and issued for public comments onJanuary 29, 2022, and officially approved on May 11, 2022, according toNo. 2 of 2022.
8	Trehalase	Trichoderma reesei	Trichoderma reesei	Accepted on September 17, 2021, Acceptance number: 卫食添新申字(2021)第0041号. Passed the technical review and issued for public comments onJanuary 29, 2022, and officially approved on May 11, 2022, according toNo. 2 of 2022.
9	Phospholipase A1	Aspergilus niger	Talaromyces leycettanus	Accepted on July 2, 2021, Acceptance number: 卫食添新申字(2021)第0027号. Passed the technical review and issued for public comments onDecember 8, 2021, and officially approved on May 11, 2022, according toNo. 2 of 2022.
10	Glucose oxidase	Aspergillus niger	Penicillium chrysogenum	Accepted on November 9, 2021, Acceptance number: 卫食添新申字(2021)第0052号. Passed the technical review and issued for public comments onDecember 8, 2021, and officially approved on May 11, 2022, according toNo. 2 of 2022.
11	Lactase	Bacillus subtilis	Lactobacillus delbrueckii subsp. Bulgaricus	Accepted on March 22, 2021, Acceptance number:卫食添新申字(2021)第0016号. Passed the technical review and issued for public comments onOctober 21, 2021, and officially approved on May 11, 2022, according toNo. 2 of 2022.
12	Phytase	Aspergillus niger	Aspergillus tubingensis	Accepted on August 20, 2020, Acceptance number: 卫食添新申字(2020)第0047号. Passed the technical review and issued for public comments onOctober 21, 2021, and officially approved on May 11, 2022, according toNo. 2 of 2022.
13	Lactase	Aspergillus niger	Aspergillus oryzae	Accepted on November 9, 2021, Acceptance number: 卫食添新申字(2021)第0053号. Passed the technical review and issued for public comments onApril 15, 2022, and officially approved on September 7, 2022, according toNo. 5 of 2022.

Note: the quality specifications of enzyme preparations for the food industry should meet the provisions of the National Standard for Food Safety, Food Additives, and enzyme preparations for Food Industry (GB1886.174).

3.2 List of new food additives (one type)

Name

Function

Category number

Food name/category

Maximum level (g/kg)

Acceptance information, public comment, and approval announcements

(By the end of December 2022)

Quinoline aluminium lake

Colorant

05.03

Coatings for candy and chocolate products (only for candy)

0.3 (Count as quinoline yellow)

Accepted on June 1, 2021, Acceptance number: 卫食添新申字(2021)第0020号.

Passed the technical review and issued for public comments onOctober 21, 2021, and officially approved on May 11, 2022, according toNo. 2 of 2022.

3.3 List of new food processing aids (one type)

Name

Function

Usage scope

Maximum level (g/kg)

Acceptance information, public comment, and approval announcements

(By the end of December 2022)

Sodium sulfide pentahydrate

Deacidifying agent, decolorizing agent, settling agent

Salt production process

0.065

Accepted on July 7, 2021, Acceptance number: 卫食添新申字(2021)第0030号.

Passed the technical review and issued for public comments onJanuary 29, 2022, and officially approved on May 11, 2022, according toNo. 2 of 2022.

3.4 List ofnew food nutrition enhancers (one type)

No	Name	Function	Category number	Food name/category	Maximum level (mg/kg)	Acceptance information, public comment, and approval announcements (By the end of December 2022)
1	Inositol	Nutrition enhancer	01.03.02	Modified milk powder (limited to milk powder for children)	210 ~250	Accepted on July 8, 2021, Acceptance number: 卫食添新申字(2021)第0033号. Passed the technical review and issued for public comments onOctober 21, 2021, and officially approved on May 11, 2022, according toNo. 2 of 2022.
			14.02.03	Fruit and vegetable juice (meat) beverages (including fermented products)	60 ~120
			14.04.02.02	Flavored beverages	60 ~120
			13.0	Special dietary food	Meet the relevant standards of special dietary food

3.5 List of food additives with expanded use (13 types)

No	Name	Function	Category number	Food Name/ Category	Maximum level (g/kg)	Acceptance information, public comment, and approval announcements (By the end of December 2022)
1	Silicon dioxide	anticaking agent	04.04.03	Other soy products (only for soy protein powder and blended soy protein powder)	15.0	Accepted on May 27, 2021, Acceptance number: 卫食添新申字(2021)第0019号. Passed the technical review and issued for public comments onAugust 6, 2021, and officially approved on March 1, 2022, according toNo. 1 of 2022.
2	Carbon dioxide	Other	01.02.02	Flavored fermented milk	Appropriate level	Its acceptance information could not be confirmed. Passed the technical review and issued for public comments onAugust 6, 2021, and officially approved on March 1, 2022, according toNo. 1 of 2022.
3	Turmeric	Colorant	06.03.02.04	Flour pastes (e.g., drag flour pastes used for fish, and poultry), breading and frying flour	0.25 (Count as curcumin)	Accepted on May 17, 2021, Acceptance number: 卫食添新申字(2021)第0018号. Passed the technical review and issued for public comments onAugust 6, 2021, and officially approved on March 1, 2022, according toNo. 1 of 2022.
4	Nisin	Preservative	04.04.01.03.02	Pot-stewed semi-dried tofu	0.5	Accepted on June 16, 2021, Acceptance number: 卫食添新申字(2021)第0024号. Passed the technical review and issued for public comments onAugust 6, 2021, and officially approved on March 1, 2022, according toNo. 1 of 2022.
5	Sucralose	Sweetener	04.04.01.05	New soy products (including puffed soy protein food and soybean meat, )	0.4	Accepted on April 12, 2021, Acceptance number: 卫食添新申字(2021)第0017号. Passed the technical review and issued for public comments onAugust 6, 2021, and officially approved on March 1, 2022, according toNo. 1 of 2022.
6	Vegetable carbon black	Colorant	01.02.02	Flavored fermented milk	5.0	Accepted on March 15, 2021, Acceptance number: 卫食添新申字(2021)第0012号. Passed the technical review and issued for public comments onAugust 6, 2021, and officially approved on March 1, 2022, according toNo. 1 of 2022.
6	Vegetable carbon black	Colorant	04.01.02.05	Jam	5.0
7	Glutamine transaminase	Stabilizer and coagulant	01.02.02	Flavored fermented milk	0.3	Accepted on January 20, 2021, Acceptance number: 卫食添新申字(2021)第0005号. Passed the technical review and issued for public comments onApril 12, 2021, and officially approved on May 11, 2022, according toNo. 2 of 2022.
7	Glutamine transaminase	Stabilizer and coagulant	01.06.01	Unripened cheese	0.3
8	Magnesium chloride	Flavoring agent	06.07	Instant rice and flour products	Appropriate level	Accepted on September 11, 2021, Acceptance number: 卫食添新申字(2020)第0057号. Passed the technical review and issued for public comments onOctober 21, 2021, and officially approved on May 11, 2022, according toNo. 2 of 2022.
			06.08	Frozen rice and flour products
			12.10	Compound condiment
9	Sucralose	Sweetener	01.06.04	Processed cheese	0.2	Accepted on September 22, 2021, Acceptance number: 卫食添新申字(2021)第0043号. Passed the technical review and issued for public comments onDecember 8, 2021, and officially approved on May 11, 2022, according toNo. 2 of 2022.
10	Lutein	Colorant	01.01.03	Modified milk	0.05	Accepted on June 29, 2021, Acceptance number: 卫食添新申字(2021)第0026号. Passed the technical review and issued for public comments onOctober 21, 2021, and officially approved on May 11, 2022, according toNo. 2 of 2022.
10	Lutein	Colorant	01.02.02	Flavored fermented milk	0.05
11	Acesulfame potassium	Sweetener	07.03	Crackers	0.6	Accepted on June 4, 2021, Acceptance number: 卫食添新申字(2021)第0022号. Passed the technical review and issued for public comments onJanuary 29, 2022, and officially approved on May 11, 2022, according toNo. 2 of 2022.
12	Tomato red	Colorant	09.02.03	Frozen surimi and its products (including fish balls)	0.08 (Measured as Lycopene)	Accepted on September 22, 2021, Acceptance number: 卫食添新申字(2021)第0044号. Passed the technical review and issued for public comments onDecember 8, 2021, and officially approved on September 7, 2022, according toNo. 5 of 2022.
12	Tomato red	Colorant	09.04	Cooked aquatic products (Can be directly consumed)	0.08 (Measured as Lycopene)
13	Carmine cochineal	Colorant	08.02.01	Conditioned meat products (raw meat with added ingredients)	0.08 (Count as carminic acid)	Accepted on January 30, 2022, Acceptance number: 卫食添新申字(2022)第0003号. Passed the technical review and issued for public comments onApril 15, 2022, and officially approved on September 7, 2022, according toNo. 5 of 2022.

2.6 List of approved processing aids with expanded use (three types)

No	Name	Function	Usage scope	Acceptance information, public comment, and approval announcements (By the end of December 2022)
1	White mineral oil	Release agent, lubricating agent	Processing technology of fresh yeast products (The maximum level is 0.1 g/kg)	Accepted on November 24, 2020, Acceptance number: 卫食添新申字(2020)第0070号. Passed the technical review and issued for public comments onAugust 6, 2021, and officially approved on March 1, 2022, according toNo. 1 of 2022.
2	Polyacrylamide	Flocculant	Salt product process	Accepted on July 17, 2020, Acceptance number: 卫食添新申字(2020)第0039号. Passed the technical review and issued for public comments onOctober 21, 2021, and officially approved on May 11, 2022, according toNo. 2 of 2022.
3	Polydimethyl siloxane and emulsion	Defoamer	Production and processing technology of yeast-processed products (maximum usage of 0.1 g/kg, counts as polydimethylsiloxane)	Accepted on November 11, 2021, Acceptance number: 卫食添新申字(2021)第0054号. Passed the technical review and issued for public comments onDecember 8, 2021, and officially approved on May 11, 2022, according toNo. 2 of 2022.

Name

Function

Usage scope

Acceptance information, public comment, and approval announcements

(By the end of December 2022)

White mineral oil

Release agent, lubricating agent

Processing technology of fresh yeast products (The maximum level is 0.1 g/kg)

Accepted on November 24, 2020, Acceptance number: 卫食添新申字(2020)第0070号.

Passed the technical review and issued for public comments onAugust 6, 2021, and officially approved on March 1, 2022, according toNo. 1 of 2022.

Polyacrylamide

Flocculant

Salt product process

Accepted on July 17, 2020, Acceptance number: 卫食添新申字(2020)第0039号.

Passed the technical review and issued for public comments onOctober 21, 2021, and officially approved on May 11, 2022, according toNo. 2 of 2022.

Polydimethyl siloxane and emulsion

Defoamer

Production and processing technology of yeast-processed products (maximum usage of 0.1 g/kg, counts as polydimethylsiloxane)

Accepted on November 11, 2021, Acceptance number: 卫食添新申字(2021)第0054号.

Passed the technical review and issued for public comments onDecember 8, 2021, and officially approved on May 11, 2022, according toNo. 2 of 2022.

Conclusion

The 2'-fucosyl lactose (2’FL) from modified E-coli was released for public comments by CFSA on April 15, 2022, which was a big step forward for the application of genetically modified microorganisms (GMM) food additives in China, and it can be expected that 2’-FL will get the approval in China soon. New food enzymes account for almost 1/3 of the food additives reviewed and approved in 2022, and most of the food enzymes are genetically modified. On December 8, 2022, the CFSA publicly solicited opinions on D-psicose-3-epimerase, whose donor bacteria were specific to the strain number.

Furthermore, it can be found that the registration period for some products is quite short. For example, it only takes about six months for glucose oxidase to receive the final approval for its acceptance by the NHC, which can be seen that if the application dossiers are well-prepared, the product can pass the technical review once and receive the final approval quickly. So, it is suggested that the applicant pays attention to the preparation of materials before submitting them to NHC.

Note: there may be omissions and errors in the data statistics process because of the change of official websites. The data in this article is for reference only, please refer to the official information published by government departments.

If you need any assistance or have any questions, please get in touch with us viaservice@cirs-group.com.